Sri Nayanananda Thakur is the nephew and dear disciple of Sri Gadadhara Pandita. Gadadhar Pandita's younger brother was Sri Vaninatha whose two sons names were Nayanananda and Hrdayananda. The descendents of Nayanananda are still living at Bharatpur, near Kandi, within the district of Murshidabad.
It is described in Prem Vilasa that Gadadhara Pandita called Nayanananda to his bedside as he was about to depart from this world. He told him, "I am entrusting to your care Sri Gopinathji and this copy of Bhagavad Gita in which, as I was copying the verses onto palm leaves, Sriman Mahaprabhu came and also wrote one verse in his own hand."
There was also a small Deity of Gopinatha which Gadadhara used to wear around his neck. Because he couldn't bear separation from the Lord, he always kept this Deity aroung his neck. This he also gave to Nayanananda who brought both Gopinatha forms to Bharatpur. There They are still nicely worshiped by the descendents of Nayanananda Thakur.
Nayanananda is mentioned in Sri Caitanya-caritamrta as Misra Nayana. His previous name might have been Dhruvananda. There is a story that when Sri Sri Gaura-Gadadhara would perform kirtan in the ecstasy of their internal emotions, Sri Dhruvanath would write down the words simply hearing them for the first time. Thus he became the object of their mercy and was bestowed the name Nayanananda. He was present at the Kheturi Utsava. In Braja-lila he was Nitya manjari.